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Cytidine-5′-monophosphate (CMP), babu acid CAS:63-37-6
Cytidine 5'-monophosphate (CMP) wani nau'in nucleotide ne wanda ke aiki a matsayin tubalin gini don haɗa RNA da gyare-gyare. Yana da muhimmin sashi a cikin gina ƙwayoyin RNA kuma yana da hannu a cikin ayyuka kamar capping mRNA da metabolism na nucleotide. Haka kuma ana amfani da CMP a cikin binciken halittu na biochemical da molecular don aikace-aikace kamar rubutun in vitro da labeling nucleic acid. Matsayinsa a cikin metabolism na RNA da amfani da shi a cikin dabarun gwaji daban-daban ya sa ya zama kayan aiki mai mahimmanci wajen fahimtar tsari da aikin ƙwayoyin RNA.
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IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4
3-isobutyl-1-methylxanthine, wanda kuma aka sani da IBMX, wani sinadari ne na methylxanthine wanda aka saba amfani da shi a binciken kimiyya a matsayin wani abu da ba shi da takamaiman tasiri ga cyclic nucleotide phosphodiesterases. An san shi yana ƙara matakan cyclic AMP (cAMP) da cyclic GMP (cGMP) a cikin ƙwayoyin halitta ta hanyar hana rushewar su, wanda hakan zai iya daidaita hanyoyin siginar ƙwayoyin halitta daban-daban.
Baya ga aikace-aikacen bincike da take yi, an yi amfani da IBMX a wasu wuraren kiwon lafiya don tasirin bronchodilator da vasodilator. Duk da haka, amfani da shi a cikin maganin ɗan adam yana da iyaka.
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4-Nitrophenyl phosphate disodium gishiri hexahydrate CAS:4264-83-9
4-Nitrophenyl phosphate disodium gishiri hexahydrate wani sinadari ne da ake amfani da shi a binciken sinadarai da magunguna. Siffa ce ta gishiri ta 4-nitrophenyl phosphate, wadda ke ɗauke da sodium ions guda biyu da ƙwayoyin ruwa guda shida. Ana amfani da wannan sinadari a matsayin wani sinadari don gwajin phosphatase da kuma nazarin motsin enzymes.
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5′-Deoxy-5-fluorocytidine CAS:66335-38-4
5′-Deoxy-5-fluorocytidine wani nau'in nucleoside ne da ake amfani da shi wajen gano yiwuwar tasirinsa na kashe ƙwayoyin cuta, musamman a kan ƙwayoyin cuta na RNA kamar cutar hepatitis C (HCV) da flaviviruses. Yana aiki ta hanyar hana kwafi na ƙwayoyin cuta, a ƙarshe yana hana ikon ƙwayar cuta ta ninka da yaɗuwa a cikin jiki.
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Cytidine-5′-triphosphate (CTP), gishirin disodium CAS:652154-13-7
Gishirin disodium, wanda aka fi sani da Cytidine-5′-triphosphate (CTP), wani sinadari ne na nucleoside triphosphate wanda ke aiki a matsayin tubalin gina RNA. Yana taka muhimmiyar rawa a cikin metabolism na tantanin halitta kuma yana da mahimmanci don canja wurin bayanan kwayoyin halitta daga DNA zuwa RNA yayin kwafi. Ana amfani da CTP sosai a cikin binciken ilmin kwayoyin halitta, musamman a cikin nazarin da ya shafi hada RNA, tsangwama na RNA, da sauran hanyoyin da suka shafi RNA. Bugu da ƙari, ana amfani da shi a cikin halayen enzymatic, nazarin metabolism na nucleotide, da kuma azaman madadin gwaje-gwajen biochemical daban-daban. A cikin masana'antar magunguna, CTP na iya samun damar amfani da shi wajen haɓaka magungunan rigakafi da maganin ciwon daji.
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ITP, inosine 5′-triphosphate gishirin trisodium CAS:35908-31-7
Gishirin trisodium na Inosine-5′-triphosphate, wanda aka fi rage shi a matsayin ITP-Na3, nau'in triphosphate ne na inosine, wani nucleoside wanda ke taka muhimmiyar rawa a cikin hanyoyin halittu daban-daban. Wannan sinadari sinadari ne na gishiri, wanda ke sa shi narkewa cikin ruwa kuma ya dace da amfani a cikin gwaje-gwajen sinadarai da enzymatic, da kuma a cikin binciken ilmin kwayoyin halitta. Ana amfani da gishirin trisodium na Inosine-5′-triphosphate don nazarin halayen enzymatic, canjin nucleotide, da kuma matsayin substrate ga wasu enzymes. Aikace-aikacensa kuma ya shafi nazarin analog na nucleotide da kuma a matsayin wani ɓangare na shirya gaurayen nucleotide da ake amfani da su a cikin dabarun ilmin kwayoyin halitta.
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5-Bromouracil CAS:51-20-7 Farashin Mai Masana'anta
5-Bromouracil wani sinadari ne na roba na uracil, wanda wani sinadari ne na RNA. Ana iya haɗa Bromouracil cikin ƙwayoyin nucleic kuma yana iya haifar da maye gurbi ta hanyar rashin daidaituwa da guanine yayin kwafi na DNA. Ana amfani da shi azaman maye gurbi a cikin binciken kwayoyin halitta don nazarin yawan maye gurbi da hanyoyin aiki.
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5-Fluoro-2′-deoxyuridine CAS:50-91-9
5-Fluoro-2′-deoxyuridine wani nau'in nucleoside ne na roba wanda ke hana haɗakar DNA. An yi nazari a kansa saboda yuwuwar tasirinsa na maganin ƙwayoyin cuta da kuma maganin ƙari. Bugu da ƙari, ana amfani da shi azaman kayan aiki na bincike a fannin ilmin kwayoyin halitta da kuma ilmin sunadarai.
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Gishirin disodium na Cytidine-5′-triphosphate CAS:36051-68-0
Gishirin disodium na Cytidine-5′-triphosphate (CTP-Na2) wani sinadarin nucleoside triphosphate ne wanda ke aiki a matsayin tubalin gina jiki a cikin hada RNA. Yana taka muhimmiyar rawa a cikin metabolism na tantanin halitta, yana aiki a matsayin substrate ga RNA polymerases a cikin rubutun bayanai da kuma tushen kuzari ga nau'ikan halayen enzymatic. Ana amfani da CTP-Na2 sau da yawa a cikin binciken halittu na biochemical da molecular a matsayin wani ɓangare na halayen da suka shafi hada RNA, gyare-gyare, da kuma daidaita su. Siffar gishirin disodium ɗinsa yana ƙara narkewar sa a cikin ruwan da ke cikin ruwan, wanda hakan ya sa ya fi dacewa da amfani da dakin gwaje-gwaje.
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Ribonucleic acid daga Baker's Yeast CAS:63231-63-0
Ribonucleic acid (RNA) daga yisti na Baker, wanda kuma aka sani da Saccharomyces cerevisiae, yana nufin ƙwayoyin RNA da ke cikin wannan naman gwari mai ƙwayoyin halitta ɗaya. Yana hidima ga ayyuka daban-daban masu mahimmanci a cikin tantanin halitta, gami da haɗa furotin, aikin enzymatic, da kuma daidaita kwayoyin halitta. RNA daga yisti na Baker yana da sha'awa ga masana kimiyya da masu bincike da ke nazarin ilimin halittar kwayoyin halitta, kwayoyin halitta, da hanyoyin tantanin halitta. Ana amfani da shi a cikin gwaje-gwaje da bincike iri-iri don samun fahimta game da bayyanar kwayoyin halitta, sarrafa RNA, da hanyoyin tantanin halitta da ke ƙarƙashin ayyukan tantanin halitta.
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6-Chloropurine CAS:87-42-3 Farashin Mai Masana'anta
6-Chloropurine wani sinadari ne da ke cikin dangin purine. Yana da sinadarin purine, wanda muhimmin sashi ne na DNA da RNA. 6-Ana amfani da Chloropurine wajen hada sinadarai na halitta da kuma binciken magunguna a matsayin wani abu da zai taimaka wajen shirya nau'ikan sinadaran purine da kuma magungunan da ke cikinsa.
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Gishirin disodium na Adenosine 5′-monophosphate CAS:4578-31-8
Gishirin disodium na Adenosine 5′-monophosphate, wanda kuma aka sani da 5′-AMP, wani nucleotide ne wanda ya ƙunshi adenine, ribose, da rukunin phosphate. Yana aiki a matsayin abin da zai fara samar da adenosine triphosphate (ATP), wanda muhimmin kwayar halitta ce da ke da hannu a canja wurin makamashin tantanin halitta. A cikin bincike da aikace-aikacen sinadarai, ana amfani da 5′-AMP a matsayin wani abu mai kama da juna a cikin halayen enzymatic, musamman a cikin nazarin metabolism na nucleotide, hanyoyin sigina, da kuma a matsayin wani ɓangare a cikin gwaje-gwaje daban-daban. Siffar gishirin disodium ɗinsa tana ƙara narkewa da kwanciyar hankali, wanda hakan ya sa ya dace da amfani da shi a gwaji.
