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Tetracycline CAS:60-54-8
Tetracycline wani maganin rigakafi ne mai faɗi wanda ke cikin ajin tetracycline, wanda aka samo daga mahaɗin halitta na chlortetracycline. Yana hana haɗakar furotin na ƙwayoyin cuta ta hanyar ɗaurewa da ribosome na ƙwayoyin cuta, ta haka yana hana haɗewar aminoacyl-tRNA zuwa mahaɗin mRNA-ribosome. Wannan hanyar aiki tana haifar da tasirin bacteriostatic akan nau'ikan ƙwayoyin cuta masu yawa na gram-positive da gram-negative, da kuma wasu protozoa.
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Teicoplanin CAS:61036-62-2
Teicoplanin maganin rigakafi ne na glycopeptide wanda aka samo daga Actinoplanes teichomyceticus, yana da tasiri akan ƙwayoyin cuta daban-daban na gram-positive ciki har da Staphylococcus aureus mai juriya ga methicillin (MRSA). Yana hana haɗakar bangon ƙwayoyin cuta ta hanyar ɗaurewa da ƙarshen D-alanyl-D-alanine na abubuwan da suka fara haifar da peptidoglycan, wanda ke haifar da lalata ƙwayoyin cuta da tasirin ƙwayoyin cuta. Sau da yawa ana amfani da Teicoplanin a wuraren asibiti don magance cututtuka masu tsanani da ƙwayoyin cuta masu gram-positive ke haifarwa.
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Sulfisoxazol (4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide) CAS:127-69-5
Sulfisoxazole, wanda aka fi sani da sulfifurazole, maganin rigakafi ne na sulfonamide wanda ke cikin rukunin magungunan sulfa. An kwatanta shi da sinadarai a matsayin 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, sulfisoxazole yana hana haɓakar ƙwayoyin cuta ta hanyar tsoma baki ga haɗakar folic acid. Wannan tsarin aiki yana kai hari ga dihydropteroate synthase, wani enzyme da ke da mahimmanci ga samar da ƙwayoyin cuta na folate, wanda hakan ke hana haɓakarsu da haɓaka su.
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Sulfapyridine CAS:144-83-2
Sulfapyridine maganin rigakafi ne na sulfonamide wanda aka yi amfani da shi a tarihi wajen magance cututtukan ƙwayoyin cuta, musamman a lokacin Yaƙin Duniya na Biyu. Yana cikin rukunin magungunan sulfa, waɗanda ke hana haɓakar ƙwayoyin cuta ta hanyar tsoma baki ga haɗakar folic acid. Sulfapyridine yana yin tasirinsa na bacteriostatic ta hanyar niyya ga dihydropteroate synthase, wani enzyme da ke da mahimmanci don samar da folate a cikin ƙwayoyin cuta.
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Tazobactam CAS:89786-04-9
Tazobactam wani maganin hana beta-lactamase ne wanda ke haɓaka aikin maganin rigakafi na beta-lactam ta hanyar kare su daga lalacewa ta hanyar enzymes na beta-lactamase da ƙwayoyin cuta da yawa masu juriya ke samarwa. Ana amfani da shi akai-akai tare da maganin rigakafi na beta-lactam kamar piperacillin don faɗaɗa tasirinsu akan cututtukan ƙwayoyin cuta iri-iri. Tazobactam yana dawo da ingancin maganin rigakafi na beta-lactam akan ƙwayoyin cuta masu samar da beta-lactamase, musamman ƙwayoyin cuta masu gram-negative.
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Tigecycline CAS:220620-09-7
Tigecycline wani maganin rigakafi ne mai faɗi wanda ke hana haɗa furotin na ƙwayoyin cuta ta hanyar ɗaure shi da sashin ribosomal na 30S, ta haka yana yin tasirin bacteriostatic akan nau'ikan ƙwayoyin cuta masu gram-positive da gram-negative, gami da ƙwayoyin cuta masu jure wa magunguna da yawa. Yana da alaƙa da tsarin tetracyclines amma yana da ingantaccen aiki akan nau'ikan ƙwayoyin cuta masu jure wa saboda tsarin aikinsa na musamman da gyare-gyaren tsarinsa.
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Gishirin sodium na Sulbactam CAS:69388-84-7
Gishirin sodium na Sulbactam wani maganin hana beta-lactamase ne wanda ake amfani da shi akai-akai tare da wasu magungunan rigakafi don yaƙar cututtukan ƙwayoyin cuta. Yana aiki ta hanyar hana ayyukan enzymes na beta-lactamase da ƙwayoyin cuta ke samarwa, waɗanda zasu iya sa maganin rigakafi ya yi tasiri. Ta hanyar hana lalacewar maganin rigakafi kamar penicillin da cephalosporins, gishirin sodium na sulbactam yana taimakawa wajen haɓaka halayensu na kashe ƙwayoyin cuta. Sau da yawa ana amfani da wannan mahaɗin tare da maganin rigakafi kamar ampicillin don ƙirƙirar tasirin haɗin gwiwa akan nau'ikan ƙwayoyin cuta masu saurin kamuwa da cuta.
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Sulfadimidine CAS:57-68-1
Sulfadimidine, wanda aka fi sani da sulfamethazine, maganin rigakafi ne na sulfonamide da ake amfani da shi wajen magance cututtukan ƙwayoyin cuta. Yana cikin rukunin magungunan ƙwayoyin cuta da aka sani da magungunan sulfa, waɗanda ke aiki ta hanyar hana haɓakar ƙwayoyin cuta da kwafi. Sulfadimidine yana tsoma baki ga haɗakar folic acid a cikin ƙwayoyin cuta, muhimmin sashi don rayuwarsu, wanda ke haifar da tasirin bacteriostatic akan nau'ikan ƙwayoyin cuta masu gram-positive da gram-negative.
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Gishirin sodium na Sulfacetamide CAS:6209-17-2
Gishirin sodium na Sulfacetamide wani sinadari ne da ke narkewa cikin ruwa daga sulfacetamide, wani maganin rigakafi na sulfonamide wanda ake amfani da shi a cikin maganin shafawa don magance cututtukan ƙwayoyin cuta na fata da idanu. Wannan sinadarin gishirin yana ƙara narkewa da kwanciyar hankali na sulfacetamide, wanda hakan ya sa ya dace da amfani da magunguna daban-daban. Gishirin sodium na Sulfacetamide yana aiki ta hanyar hana haɓakar ƙwayoyin cuta, musamman waɗanda ke da alhakin cututtuka kamar kuraje vulgaris, seborrheic dermatitis, da cututtukan ido kamar conjunctivitis. Yana tsoma baki ga haɗakar ƙwayoyin cuta na folate, yana mai da hankali kan nau'ikan ƙwayoyin cuta masu gram-positive da gram-negative.
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Streptomycin sulfate CAS:3810-74-0
Streptomycin sulfate magani ne na maganin rigakafi wanda ke cikin rukunin aminoglycoside. An samo shi ne daga ƙwayar cuta ta Streptomyces griseus kuma ana amfani da shi sosai don magance cututtukan ƙwayoyin cuta. Streptomycin sulfate yana aiki ta hanyar hana haɗakar furotin na ƙwayoyin cuta, ta haka yana kashe ƙwayoyin cuta masu saurin kamuwa da cuta yadda ya kamata. Sau da yawa ana rubuta shi don maganin tarin fuka, annoba, tularemia, da wasu cututtuka da ƙwayoyin cuta masu saurin kamuwa da cuta ke haifarwa. Yawanci ana samun Streptomycin sulfate a cikin allura kuma ana ba shi ko dai ta hanyar jijiya ko ta hanyar jijiya a ƙarƙashin kulawar likita.
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Gishirin sodium na Sulfamethoxazole CAS:4563-84-2
Gishirin sodium na Sulfamethoxazole wani sinadari ne da ke narkewa cikin ruwa daga sulfamethoxazole, wani maganin rigakafi na sulfonamide da ake amfani da shi wajen magance cututtukan ƙwayoyin cuta. Wannan sinadarin gishirin yana ƙara narkewa da kwanciyar hankali na sulfamethoxazole, wanda hakan ya sa ya dace da nau'ikan magunguna daban-daban. Gishirin sodium na Sulfamethoxazole yana yin tasirinsa na bacteriostatic ta hanyar hana haɗakar folic acid a cikin ƙwayoyin cuta, wani muhimmin tsari don girma da kwafi. Yana da tasiri akan nau'ikan ƙwayoyin cuta masu yawa na gram-positive da gram-negative.
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Sulfamethoxazole CAS:723-46-6
Sulfamethoxazole maganin rigakafi ne na sulfonamide wanda aka saba amfani da shi tare da trimethoprim don ƙirƙirar maganin kashe ƙwayoyin cuta mai ƙarfi wanda aka sani da co-trimoxazole ko trimethoprim-sulfamethoxazole (TMP-SMX). Yana cikin rukunin magungunan kashe ƙwayoyin cuta da aka sani da magungunan sulfa, waɗanda ke hana haɓakar ƙwayoyin cuta ta hanyar tsoma baki ga haɗakar folic acid. Sulfamethoxazole musamman yana kai hari ga dihydropteroate synthase, wani enzyme da ke da hannu a samar da folate, ta haka yana yin tasirin bacteriostatic akan nau'ikan ƙwayoyin cuta masu gram-positive da gram-negative.
