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Lasmiditant CAS:439239-90-4
Lasmiditan, wanda aka tallata a ƙarƙashin sunan Reyvow, wani sabon sinadari ne na magunguna wanda aka tsara don rage yawan hare-haren migraine mai tsanani a cikin manya. Yana cikin rukunin masu karɓar serotonin masu zaɓin serotonin, musamman waɗanda ke mai da hankali kan nau'in mai karɓar 5-HT1F. Wannan hanyar aiki ta bambanta Lasmiditan daga magungunan migraine na gargajiya, saboda ba ya haifar da toshewar jijiyoyin jini, wanda hakan ya sa ya dace da marasa lafiya da ke da abubuwan da ke haifar da haɗarin zuciya da jijiyoyin jini.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone wani sinadari ne da aka sani da amfaninsa daban-daban a cikin hadakar sinadarai da hadewar sinadarai. Hadinsa ya kunshi amsawar N-methylcarbamoyl chloride tare da 2-chloroacetohydrazide, wanda ke haifar da wani sinadari mai siffofi daban-daban na tsari da aiki. Wannan sinadari yana da siffa ta ikon samar da hadadden sinadarai tare da ions na karfe daban-daban, wanda hakan ke sa shi zama mai amfani a nazarin sinadarai masu hadewa. Bugu da kari, rukunonin carbonyl da amidrazone suna ba da gudummawa ga amsawar sinadaransa da kuma ayyukan magunguna masu yuwuwa, wadanda su ne fannoni da ake ci gaba da sha'awar bincike.
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Lasmiditan HCl CAS:613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) wani sinadari ne na magunguna wanda aka san shi da rawar da yake takawa wajen magance hare-haren migraine mai tsanani a cikin manya. An haɓaka shi azaman mai karɓar serotonin mai zaɓi, musamman wanda ke niyya ga nau'in mai karɓar 5-HT1F, Lasmiditan HCl yana wakiltar babban ci gaba a cikin maganin migraine saboda tsarin aikinsa na musamman da ingancinsa na asibiti.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, wanda aka fi sani da aminopyridine methylpiperidone, wani sinadari ne mai mahimmanci a fannin ilmin sinadarai na magani da binciken magunguna. An haɗa shi ta hanyar amsawar 6-aminopicolinic acid tare da 1-methylpiperidin-4-one, wannan sinadari yana nuna siffofi na musamman na tsarin da ke ba da gudummawa ga ƙarfinsa na magunguna da kuma iya aiki yadda ya kamata.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-Quinuclidinol, wanda kuma aka sani da quinuclidinol, wani muhimmin sinadari ne a fannin ilmin sinadarai na halitta da binciken magunguna saboda keɓancewar tsarinsa da kuma aikace-aikacensa daban-daban. Wannan sinadari na chiral ya samo asali ne daga quinuclidine kuma yana nuna halaye daban-daban na sinadarai da magunguna waɗanda suka jawo hankali a fannoni daban-daban na kimiyya.
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MASU TSARIN MATSALAR CAS:171482-05-6
Magungunan tsaka-tsaki na Aprepitant suna taka muhimmiyar rawa a cikin haɗakar magunguna na aprepitant, wani mai hana karɓar neurokinin-1 (NK1) wanda ake amfani da shi musamman wajen hana tashin zuciya da amai da ke haifar da chemotherapy (CINV). Waɗannan magunguna masu mahimmanci ne a cikin hanyar roba mai matakai da yawa wanda ke haifar da ƙirƙirar aprepitant na ƙarshe. An san Aprepitant da kanta saboda ingancinsa wajen sarrafa CINV, yana ba da taimako mai yawa ga marasa lafiya da ke shan chemotherapy. Haɗa aprepitant ya ƙunshi matakai da yawa masu mahimmanci, tare da magunguna masu tsaka-tsaki suna aiki azaman tubalan gini waɗanda ke ba da damar samar da wannan muhimmin maganin warkewa cikin inganci.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
2,4,6-Trifluorobenzoyl chloride, wanda aka fi sani da trifluorobenzoyl chloride, muhimmin sinadari ne da ake darajawa saboda aikace-aikacensa daban-daban a cikin hadakar kwayoyin halitta da kuma hanyoyin masana'antu. An haɗa wannan sinadari ta hanyar chlorine na 2,4,6-trifluorobenzoic acid, yana nuna halaye na musamman na sinadarai waɗanda ke ba da gudummawa ga amfani da shi a fannoni daban-daban.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
4-Chloro-6-iodoquinazoline wani sinadari ne mai dauke da sinadarin C9H5ClIN2. Yana da alaƙa da kasancewar sinadarin chlorine da iodine da aka haɗa a cikin tsarin zoben quinazoline. Ana amfani da wannan sinadari a binciken magunguna da kuma haɗakar kwayoyin halitta saboda yuwuwar amfaninsa wajen ƙirƙirar sabbin magunguna da sauran ƙwayoyin halitta masu aiki a fannin halitta.
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(R)-3-Quinuclinol CAS:25333-42-0
(R)-3-Quinuclinol, wanda aka fi sani da quinuclidinol, wani muhimmin sinadari ne a fannin ilmin sinadarai na halitta da binciken magunguna saboda keɓancewar tsarinsa da kuma aikace-aikacensa daban-daban. Wannan sinadari na chiral ya samo asali ne daga quinuclidine kuma yana nuna halaye daban-daban na sinadarai da magunguna waɗanda suka jawo hankali a fannoni daban-daban na kimiyya.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Sinadarin (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate wani hadadden kwayar halitta ce mai siffofi na musamman na tsari da na magani. Yana cikin ajin morpholine na mahadi, waɗanda galibi ana amfani da su a fannin ilmin sunadarai na magani saboda bambancin ayyukansu na halitta.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzemethanamine wani sinadari ne da aka sani da amfaninsa daban-daban a cikin hadakar kwayoyin halitta da kuma sinadaran magani. An haɗa shi ta hanyar amsawar (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone tare da ammonia ko amine, wannan sinadari yana da siffofi na musamman na tsarin da ke ba da gudummawa ga bambancin aikinsa da kuma yuwuwar ayyukan magunguna.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine wani sinadari ne da aka sani da amfaninsa daban-daban a cikin hadakar kwayoyin halitta da kuma sinadaran magani. An haɗa shi ta hanyar amsawar 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone tare da ammonia ko amine, wannan sinadari yana nuna siffofi na musamman na tsarin da ke ba da gudummawa ga sauƙin aiki da kuma yuwuwar ayyukan magunguna.
