Candesartana Cilexetila CAS:145040-37-5

Candesartan Celexetil wani nau'in ester ne na Candesartan mai adawa da angiotensin II (sc-217825). Hana wannan mai karɓar maganin yana hana ɗaure angiotensin II, wani mai ƙarfi na vasoconstrictor. Wannan yana da tasirin jijiyoyin jini gaba ɗaya da kuma ƙaruwar yawan jinin capillary. Candesartan Celexetil Ester wani mai hana AT1 ne.

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Candesartan cilexetil magani ne na mai karɓar angiotensin II nau'in 1 mai ƙarfi, mai aiki na dogon lokaci, kuma mai zaɓe na mai karɓar angiotensin II nau'in AT1, candesartan. Ana samar da shi cikin sauri zuwa candesartan yayin shan gastrointestinal. Bayan hydrolysis na candesartan cilexetil zuwa candesartan yayin shan gastrointestinal, candesartan yana yin gogayya da angiotensin II don ɗaure nau'in mai karɓar angiotensin II nau'in 1 AT1 a cikin tsokoki masu santsi na jijiyoyin jini, yana toshe vasoconstriction na angiotensin II da kuma haifar da vasodilatation. Bugu da ƙari, ƙin yarda da AT1 a cikin glandar adrenal yana hana haɗakar aldosterone da angiotensin II ke yi da kuma fitar da shi ta hanyar adrenal cortex; yawan fitar sodium da ruwa yana ƙaruwa, sannan kuma rage yawan jini da hawan jini.

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Ƙarin Bayani:

Tsarin aiki	C33H34N6O6
Gwaji	99%
Bayyanar	Foda Fari
Lambar CAS	145040-37-5
shiryawa	1KG 25KG
Rayuwar shiryayye	Shekaru 2
Ajiya	A adana a wuri mai sanyi da bushewa
Takardar shaida	ISO.