Candesartan CAS:139481-59-7 Mai Kaya na Masana'anta

Candesartan wani zaɓi ne na AT1 (angiotensin II receptor 1). Hana masu karɓar angiotensin yana hana vasoconstriction da samar da aldosterone, wanda ke haifar da raguwar yawan ruwa da sodium a cikin jini. Yana nuna tasirin hana hawan jini a cikin samfuran dabbobi. Ana amfani da shi wajen magance matsalar toshewar zuciya, a matsayin maganin hawan jini. Candesartan ba ya shafar yuwuwar ƙwayoyin halitta ko yaduwa amma yana ƙara yawan VEGF da interleukin-8 a cikin hanyar da aka haɓaka ta ƙwayoyin KU-19-19. Candesartan (0.1 nM) na iya rage mafi girman martanin da ake samu ga angiostensin II da kusan kashi 50%.