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1 '1-Bis(diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, tare da dabarar sinadarai [Pd(dppf)Cl₂·CH₂Cl₂], wani sinadari ne na organometallic wanda ke dauke da palladium(II) wanda aka hade shi da dppf ligand da chlorides a cikin wani sinadari na dichloromethane. Ana amfani da shi sosai wajen hada kwayoyin halitta da kuma hada su.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea wani sinadari ne da ke nuna kasancewar ƙungiyar aiki ta thiourea da aka haɗa da wani ɓangare na 6-bromopyridin-2-yl. Wannan sinadari ya sami sha'awa a fannin kimiyyar magunguna saboda ayyukansa daban-daban na magunguna da kuma yuwuwar amfani da su wajen warkar da cututtuka. Sifofinsa na musamman na tsarin suna ba da hanyoyi don ƙirƙirar sabbin masu neman magani tare da takamaiman manufofin halittu, wanda hakan ya sa ya zama babban kadara a cikin gano magunguna da haɓaka su.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, wanda aka fi sani da TMDBP, wani sinadari ne na sinadarai wanda ya samo asali daga ajin esters na phenolic boronic. Tsarin kwayoyin halittarsa ya ƙunshi ƙungiyar phenolic hydroxyl da aka haɗa zuwa zoben phenyl wanda ke ɗauke da ɓangaren ester mai ɗauke da boron. Wannan sinadari yana da mahimmanci a cikin haɗakar kwayoyin halitta, musamman a cikin halayen haɗin gwiwa na Suzuki-Miyaura, inda yake aiki a matsayin reagent na boronic ester mai mahimmanci. Bugu da ƙari, tsarinsa mai karko na boronate mai cyclic da yanayin da aka hana shi sterically ya sa ya zama da amfani wajen tsara ligands don halayen da aka canza na ƙarfe da kuma haɓaka kayan aiki.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS:761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester wani sinadari ne da aka rarraba shi azaman boronic ester. Tsarin kwayoyin halittarsa ya ƙunshi wani sinadari na boronic acid da aka haɗa zuwa zoben pyrazole wanda aka maye gurbinsa da rukunin pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Wannan sinadari yana da matuƙar muhimmanci a cikin haɗakar kwayoyin halitta, musamman a cikin halayen haɗin gwiwa na Suzuki-Miyaura, inda yake aiki azaman reagent na boronic ester mai amfani. Bugu da ƙari, kwanciyar hankali, amsawar zaɓi, da dacewa da yanayi daban-daban na amsawa sun sa ya zama mai mahimmanci a cikin haɗakar magunguna, sinadarai na agrochemicals, da kayan aiki.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- wani sinadari ne mai haɗakar keke tare da tsarin cyclopenta[b]pyrrole core da kuma sarkar gefen hexahydro-1H-pyrrole-3a(1H)-methanol. Wannan kwayar halitta tana da mahimmanci a fannin ilmin likitanci saboda yuwuwar ayyukanta na magani. Tsarinta na musamman yana ba da dama ga ci gaban sabbin masu neman magani, musamman waɗanda ke mai da hankali kan cututtukan jijiyoyi da sauran cututtuka inda daidaita masu karɓar neurotransmitter da masu jigilar kaya yake da mahimmanci. Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- yana aiki a matsayin mafari ga masana kimiyyar magunguna waɗanda ke bincika sabbin magungunan warkewa tare da ingantattun kaddarorin pharmacokinetic da rage tasirin illa.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid wani hadadden kwayar halitta ne wanda ke dauke da zoben pyrrolidine wanda aka maye gurbinsa da kungiyar tert-butoxycarbonyl a matsayi na 1 da kuma kungiyar phenyl 3-(trifluoromethyl) a matsayi na 4. Wannan hadadden yana da mahimmanci a fannin ilmin likitanci, musamman saboda yuwuwar sa a matsayin maganin magunguna a tsarin magunguna. Tsarin sa mai rikitarwa yana gabatar da damammaki don ƙirƙirar sabbin magungunan warkarwa tare da keɓaɓɓun kaddarorin magunguna, musamman hanyoyin da ke da alaƙa da cututtukan kumburi, ciwon daji, ko matsalolin tsarin jijiyoyi na tsakiya.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride wani sinadari ne da ke da siffa ta zoben pyrrolidine da aka maye gurbinsa da rukunin ethyl a matsayi na 3 da kuma rukunin tert-butyl a matsayi na 1. Wannan sinadari ya jawo hankali a fannin kimiyyar magunguna saboda tsarin sitiriyo da kuma yuwuwar amfani da shi wajen magance cututtuka. Tsarinsa na musamman yana samar da hanyoyi don tsara sabbin masu neman magani tare da takamaiman manufofin halittu, wanda hakan ya sanya shi zama kadara mai mahimmanci a cikin binciken magunguna da kuma ci gaba da ayyukan.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride wani sinadari ne da aka bambanta shi da zoben pyrrolidine wanda aka maye gurbinsa da rukunin ethyl a matsayi na 3 da kuma ƙungiyar tert-butyl a matsayi na 1. Wannan sinadari ya jawo hankali a fannin kimiyyar magunguna saboda sarkakiyar tsarinsa da kuma yuwuwar amfani da shi wajen sarrafa magunguna. Tsarinsa na musamman yana ba da damammaki don ƙirƙirar sabbin masu neman magani tare da takamaiman manufofin halittu, wanda hakan ya sa ya zama babban kadara a cikin binciken magunguna da ƙoƙarin haɓaka su.
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4-Hydroxyphenylboronic acid pinacol ester CAS:269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, wanda aka fi sani da 4-HPBA pinacol ester, wani sinadari ne da ke ƙarƙashin rukunin esters na boronic. Tsarin kwayoyin halittarsa ya ƙunshi wani sinadari na boronic acid da aka haɗa da zoben phenyl wanda aka maye gurbinsa da ƙungiyar pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Wannan sinadari yana da matuƙar muhimmanci a cikin haɗakar kwayoyin halitta, musamman a cikin halayen haɗin gwiwa na Suzuki-Miyaura, inda yake aiki a matsayin sinadari na boronic ester mai amfani da yawa. Bugu da ƙari, kwanciyar hankalinsa, sauƙin sarrafawa, da kuma dacewa da yanayi daban-daban na amsawa sun sa ya zama mai mahimmanci a cikin haɗakar magunguna, samfuran halitta, da kayan aiki.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride wani sinadari ne wanda ya ƙunshi ƙungiyar aiki ta carbamate da aka haɗa zuwa zoben piperidine wanda aka maye gurbinsa da ƙungiyar benzyl a cikin atom na nitrogen da kuma ƙungiyar propyl a cikin atom na carbon. Wannan sinadari ya jawo sha'awa ga ilimin sinadarai na magani saboda sarkakiyar tsarinsa da yuwuwar amfani da shi wajen maganin cututtuka. Tsarinsa na musamman yana ba da damammaki don ƙirƙirar sabbin masu neman magani tare da takamaiman manufofin halittu, wanda hakan ya sa ya zama babban kadara a cikin binciken magunguna da ƙoƙarin haɓaka su.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic acid CAS:333432-28-3
9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, wanda aka fi sani da DMFBA, wani sinadari ne na sinadarai wanda ke cikin ajin boronic acid. Tsarin kwayoyin halittarsa yana da wani sinadari na boronic acid da aka haɗe da wani sinadari na fluorene wanda aka maye gurbinsa da ƙungiyoyin methyl guda biyu a matsayi na 9. Wannan sinadari yana da matuƙar muhimmanci a cikin haɗakar kwayoyin halitta, musamman a cikin halayen haɗin gwiwa na Suzuki-Miyaura, inda yake aiki a matsayin sinadari mai amfani da boronic acid. Bugu da ƙari, tsarinsa mai tauri da hana steryl ya sa ya zama mai mahimmanci a cikin ƙirar ligand don halayen da aka canza ta hanyar ƙarfe da kuma haɓaka kayan aiki.
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4-Carboxyphenylboronic acid CAS:14047-29-1
4-Carboxyphenylboronic acid, wanda aka fi sani da 4-Carboxyphenylboronic acid ko 4-CPBA, wani sinadari ne na sinadarai wanda ke cikin ajin boronic acid. An siffanta shi da ƙungiyar aiki ta boronic acid (-B(OH)₂) da aka haɗa da zoben phenyl wanda aka maye gurbinsa da ƙungiyar carboxylic acid (-COOH) a matsayin para. Wannan sinadari yana samun aikace-aikace masu yawa a cikin haɗakar halitta, musamman a cikin halayen haɗin gwiwa na Suzuki-Miyaura don samar da haɗin carbon-carbon. Bugu da ƙari, ikon ɗaure shi da diols da sukari ya haifar da amfani da shi wajen haɓaka na'urori masu auna glucose da kuma a cikin kimiyyar magunguna don ƙirƙirar masu hana enzyme da ligands masu karɓa.
