VALIMOYCIN CAS:2001-95-8 Farashin Mai Masana'anta

Valinomycin wani maganin rigakafi ne na halitta wanda ake kira cyclic peptide wanda galibi ake samarwa ta hanyar wasu nau'ikan ƙwayoyin cuta na Streptomyces. Ya ƙunshi zagayowar alternating D- da L-amino acid, tare da tsarin cyclic depsipeptide na tsakiya. Valinomycin sananne ne saboda yawan kusancinsa ga monovalent cations, musamman potassium ions (K+).

Saboda iyawarsa ta ɗaure da jigilar ions na potassium a cikin membranes na halittu, valinomycin ya sami aikace-aikace daban-daban a cikin binciken kimiyya da fasahar kere-kere. Ana amfani da shi sosai a matsayin ionophore a cikin electrodes na zaɓin ions don auna yawan potassium a cikin samfuran halittu. Ikon musamman na Valinomycin na jigilar ions na potassium shi ma ya sa ya zama da amfani a cikin nazarin jigilar ions da yuwuwar membrane a cikin ƙwayoyin halitta.

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Aikace-aikace da Tasiri

Valinomycin yana aiki ne a matsayin ionophore, ma'ana yana sauƙaƙa jigilar takamaiman ions a cikin membranes na tantanin halitta. Babban tasirinsa shine ƙarfin kusancinsa ga ions na potassium (K+). Valinomycin yana samar da hadaddun abubuwa tare da ions na K+, wanda hakan ya sa ya zama zaɓi mai kyau don jigilar su.

Ɗaya daga cikin manyan aikace-aikacen valinomycin shine a matsayin ionophore a cikin electrodes na zaɓin ion don auna yawan potassium a cikin samfuran halittu. Waɗannan electrodes suna amfani da ikon valinomycin don ɗaure da jigilar ions na K+, wanda ke ba da damar auna ions na potassium daidai kuma masu laushi.

Ikon Valinomycin na jigilar ions na potassium shi ma ya sa ya zama mai amfani a cikin bincike da ya shafi jigilar ions da ƙarfin membrane a cikin ƙwayoyin halitta. Ana amfani da shi don nazarin rawar da tashoshin ions, ƙarfin membrane, da kuma gradients na ions a cikin hanyoyin halittu daban-daban.

Bugu da ƙari, an yi bincike kan valinomycin don amfanin da zai iya yi wa magani. Ya nuna sakamako mai kyau a matsayin maganin hana ciwon daji a wasu nau'ikan ciwon daji. Valinomycin yana haifar da apoptosis (mutuwar ƙwayoyin halitta) a cikin ƙwayoyin cutar kansa ta hanyar lalata ƙarfin membrane na mitochondrial.

Shirya Samfurin:

Ƙarin Bayani:

Tsarin aiki	C54H90N6O18
Gwaji	99%
Bayyanar	Foda fari
Lambar CAS	2001-95-8
shiryawa	Ƙarami da girma
Rayuwar shiryayye	Shekaru 2
Ajiya	A adana a wuri mai sanyi da bushewa
Takardar shaida	ISO.