TOP CAS: 40567-80-4 Farashin Mai ƙira

Sodium 3- (N-ethyl-3-methylanilino) propanesulfonate, wanda kuma aka sani da MESNA, yana da takamaiman tasiri da aikace-aikace a cikin kwayoyin halitta da kwayoyin halitta.Ana amfani da shi da farko azaman wakili mai ragewa don kariyar ƙungiyoyin thiol (-SH) a cikin furotin da peptides.

MESna tana aiki azaman wakili mai ƙarfi mai ragewa, mai iya juyar da haɗin gwiwar disulfide (-SS-) a cikin sunadaran zuwa ƙungiyoyin sulfhydryl (-SH).Wannan tsarin ragewa yana da mahimmanci a aikace-aikacen kimiyya daban-daban, gami da nazarin furotin, tsarkakewa, da injiniyan furotin.

Wasu takamaiman aikace-aikacen MESNA sun haɗa da:

Denaturation na Protein: Ana iya amfani da MESNA don cire sunadaran sunadaran ta hanyar karya haɗin gwiwar disulfide, ta haka buɗe tsarin furotin da sauƙaƙe ƙarin bincike ko tsarkakewar furotin.

Rage Haɗin Jiki: MESNA na iya hana haɓakar furotin ta hanyar rage haɗin disulfide, tabbatar da kwanciyar hankali na furotin da solubility a cikin bayani.

Lakabin Protein: Ana iya amfani da MESna don gabatar da lakabi ko gyare-gyare a takamaiman ragowar cysteine ​​a cikin sunadaran ta hanyar karya haɗin disulfide da fallasa ƙungiyoyin sulfhydryl (-SH).

Refolding Protein: Ana amfani da MESNA don taimakawa maimaituwar sunadaran bayan an cire shi ta hanyar rage haɗin disulfide da kuma taimakawa a ingantacciyar tsarin gina jiki.