Sodium Alpha-Ketoisocaproate CAS:4502-00-5 Mai Kaya na Masana'anta

Sodium Alpha-Ketoisocaproate wani sinadarin leucine ne wanda aka san yana haifar da fitar insulin daga ƙwayoyin β na pancreas. Ana gano cewa jiko na aα-Ketoisocaproate a cikin ciki yana rage yanayin endotoxemic. Jikin ketone da aka samu daga juyawarsa, na iya zama tushen kuzari. Tarin α-Ketoisocaproic acid yana bayyana a cikin sarkar ketoaciduria mai reshe, wanda ke faruwa ne saboda rashin aikin sarkar L-2-keto acid dehydrogenase mai reshe. α-Ketoisocaproic acid yana haifar da rabuwa a cikin amsawar oxidative phosphorylation kuma yana aiki azaman mai hana metabolism na α-ketoglutarate dehydrogenase. Don haka, yana haifar da lahani a cikin homeostasis na mitochondrial, wanda aka lura a cikin sarkar reshe ketoaciduria.