Simvastatin CAS:79902-63-9 Mai Kaya na Masana'anta

Simvastatin semi-synthetic ne, ɗan kama da lovastatin. Kamar lovastatin, simvastatin wani takamaiman mai hana HMG-CoA reductase ne kuma ana amfani da shi ta hanyar magani don rage LDL cholesterol. Kwanan nan, statins sun zama muhimman na'urori masu binciken sinadarai a cikin ilmin halittar ƙwayoyin halitta. Shigansu cikin al'amura da yawa ana iya danganta shi da babban hanyar aikinsu, duk da haka, hanyar aiwatar da wasu tasirin da yawa ba ta bayyana ba. Simvastatin takamaiman mai hana HMG-CoA reductase ne, enzyme wanda ke haɓaka canza HMG-CoA zuwa mevalonate, mataki na farko a cikin biosynthesis na cholesterol. Ana amfani da shi wajen magance hypercholesterolemia, saboda yana rage matakan lipoproteins masu ƙarancin yawa da triglycerides, kuma yana haɓaka matakan lipoprotein mai yawa.