Karin Protein Kinase KT5823 CAS:126643-37-6

Karin sinadarin kinase na furotin KT5823 ƙaramin abu ne mai hana ƙwayoyin halitta wanda ke kai hari musamman kuma yana hana ayyukan kinase na furotin. Kinase na furotin enzymes ne waɗanda ke phosphorylate sunadarai ta hanyar ƙara ƙungiyoyin phosphate zuwa takamaiman ragowar amino acid, yawanci serine, threonine, ko tyrosine. Wannan tsarin phosphorylation yana taka muhimmiyar rawa a cikin hanyoyi daban-daban na siginar ƙwayoyin halitta, yana daidaita aikin furotin, da kuma sarrafa hanyoyin ƙwayoyin halitta kamar haɓakar ƙwayoyin halitta, rarrabuwa, bambance-bambance, da apoptosis.

Ana amfani da KT5823 a cikin nazarin bincike don bincika aikin da kuma hanyoyin siginar kinases na furotin. Ta hanyar hana kinases na furotin, KT5823 na iya taimaka wa masu bincike su tantance takamaiman sunadarai da hanyoyin da aikin kinase ya shafa. Wannan bayanin zai iya zama mai fahimta wajen fahimtar rawar kinases na furotin a cikin ayyukan tantanin halitta da kuma yiwuwar gano sabbin manufofin magani.

Yi oda ko Nemi Farashi

Cikakken Bayani game da Samfurin

Alamun Samfura

Aikace-aikace da Tasiri

Karin sinadarin kinase na furotin KT5823 wani abu ne da ake amfani da shi wajen hana sinadarin kinase na furotin G (PKG), musamman wanda ke nufin nau'in isoform na I PKG-1. PKG wani sinadari ne na serine/threonine wanda ke taka muhimmiyar rawa a cikin hanyoyin ƙwayoyin halitta daban-daban kamar su sassauta tsoka mai santsi, tara ƙwayoyin platelet, da kuma daidaita vasodilation.

Babban tasirin KT5823 shine hana ayyukan PKG-1 ta hanyar yin gogayya da ATP zuwa yankin kinase. Ta hanyar hana PKG-1, KT5823 na iya kawo cikas ga hanyoyin sigina da ke ƙasa da kunna PKG-1, gami da cascades na sigina masu dogaro da cGMP.

Amfani da KT5823 galibi yana cikin binciken bincike don bincika aikin da hanyoyin siginar PKG-1. Amfani da shi wajen hana ayyukan PKG-1 yana bawa masu bincike damar bincika rawar da PKG-1 ke takawa a cikin hanyoyi daban-daban na ilimin halittar jiki da na cututtuka. Wasu takamaiman aikace-aikacen KT5823 sun haɗa da:

Binciken sassauta tsoka mai santsi: PKG-1 yana taka muhimmiyar rawa wajen sassauta tsoka mai santsi. Ta hanyar hana PKG-1 ta amfani da KT5823, masu bincike za su iya nazarin hanyoyin da ke cikin sassauta tsoka mai santsi, wanda yake da mahimmanci a fannoni kamar binciken zuciya da jijiyoyin jini.

Yin nazarin tarin platelets: PKG-1 kuma yana daidaita tarin platelets da samuwar gudan jini. Hana PKG-1 tare da KT5823 yana bawa masu bincike damar tantance tasirin ayyukan PKG-1 akan aikin platelets da kuma fahimtar hanyoyin da ke tattare da hakan.

Binciken manufofin PKG-1 na ƙasa: Ta hanyar hana PKG-1, masu bincike za su iya gano da kuma nazarin manufofin ƙasa da kuma tasirin siginar PKG-1, suna ba da haske game da hanyoyin kwayoyin halitta da ke ƙarƙashin martanin ƙwayoyin halitta da PKG-1 ke jagoranta.

Shirya Samfurin:

Ƙarin Bayani:

Tsarin aiki	C29H25N3O5
Gwaji	99%
Bayyanar	Foda fari
Lambar CAS	126643-37-6
shiryawa	Ƙarami da girma
Rayuwar shiryayye	Shekaru 2
Ajiya	A adana a wuri mai sanyi da bushewa
Takardar shaida	ISO.