Olmesartan Medoxomil CAS:144689-63-4 Mai Kaya na Masana'anta

Olmesartan Medoxomil, wani sabon mai hana karɓar angiotensin II nau'in 1 ne mai zaɓe kuma mai gasa wanda ba shi da peptide kuma yana hana martanin mai matsa lamba da Ang.ll ke haifarwa da ƙarfi. Maganin ya hana ɗaure [125I1]-All ga masu karɓar AT1 a cikin membranes na cortical na shanu, amma bai yi wani tasiri ba kan ɗaurewa ga masu karɓar AT2 a cikin membranes na cerebellar na shanu. An kuma nuna cewa Olmesartan medoxomil yana rage hawan jini sosai fiye da losartan da captopril mai hana ACE da kuma yadda ya kamata kamar pbloker atenolol.

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Olmesartan medoxomil wani maganin hana karɓar angiotensin II ne da ake amfani da shi wajen magance hawan jini. Olmesartan yana aiki ta hanyar toshe hanyar da angiotensin II ke bi ga masu karɓar AT1 a cikin tsokar jijiyoyin jini. Ta hanyar toshe hanyar da aka bi maimakon haɗa angiotensin II, olmesartan yana hana mummunan martanin ƙa'idoji kan fitar da renin. Olmesartan medoxomil magani ne mai hana maye wanda ke rage sinadarin ester ga metabolite mai aiki, olmesartan. Olmesartan yana da hanyoyi biyu na kawar da shi, inda kusan kashi 60% na hanta ke cirewa, sauran kuma koda ce ke cirewa. A cikin yanayin da aikin koda ko hanta ke raguwa, hanyar da aka bi wajen fitar da shi na iya rama wanda ya lalace.

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Ƙarin Bayani:

Tsarin aiki	C29H30N6O6
Gwaji	99%
Bayyanar	Foda fari zuwa launin shuɗi
Lambar CAS	144689-63-4
shiryawa	25KG
Rayuwar shiryayye	Shekaru 2
Ajiya	A adana a wuri mai sanyi da bushewa
Takardar shaida	ISO.