Acetyl Octapeptide-3 CAS:868844-74-0 tsari da aikace-aikace

Acetyl Octapeptide-3 (CAS 868844-74-0) sanannen peptide ne na roba a kimiyyar kwalliya, wanda galibi ana tallata shi da sunan kasuwanci na SNAP-8. Bari mu raba yadda aka tsara shi da kuma yadda ake amfani da shi dalla-dalla.

1. Asali da Tsarin Aiki

· Asalin Sinadarai:Peptide ne na roba wanda aka yi da acetylated tare da jerin Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2. Acetylation ɗin yana ƙara shigar fatarta da kwanciyar hankali.

· Babban Tsarin:Sau da yawa ana kiransa "madadin Botox na musamman," aikinsa ya dogara ne akan hana gasa. Yana kwaikwayon ƙarshen N-terminal na furotin SNAP-25, wani muhimmin sashi a cikin hadaddun SNARE wanda ake buƙata don sakin neurotransmitters (kamar acetylcholine) waɗanda ke nuna matsewar tsoka.

· Babban Tasiri:Ta hanyar yin gogayya da SNAP-25 na halitta don samun wuri a cikin hadaddun SNARE, yana hana samuwar hadaddun aiki gaba ɗaya. Wannan yana haifar da raguwar sakin neurotransmitter kaɗan, wanda ke haifar da raguwar ƙarfi da yawan matsewar tsokar fuska ta sama, ta haka yana rage bayyanar layukan bayyanannu, musamman a goshi da kewayen idanu.

2. Jagororin Tsarin

Acetyl Octapeptide-3 sinadari ne mai ƙarfi amma mai laushi. Tsarin da ya dace yana da matuƙar muhimmanci don kwanciyar hankali da inganci.

A) Shawarar Mai da Hankali:

· Matsayin amfani na yau da kullun yana tsakanin2% zuwa 10%na maganin peptide da aka riga aka narkar.

· Yawan sinadarin peptide mai aiki a cikin kayan da aka sarrafa (sau da yawa foda mai launin fari) yawanci ana daidaita shi. Masu samar da kayayyaki na yau da kullun suna samar da shi azaman2% ko 5%maganin da aka riga aka narkar (a cikin ruwa ko cakuda ruwa/glycerin) don sauƙaƙe hadawa.

· Yawan peptide mai aiki a cikin samfurin ƙarshe yawanci yana farawa daga0.0005% zuwa 0.002% (5-20 ppm)Koyaushe ku bi takamaiman shawarwarin da mai samar da kayan ku ya bayar game da yawan shan maganin.

B) Narkewa da Abin Hawa:

· Yana narkewa sosai a ruwa. Ya fi kyau a tsara shi a lokacin ruwa na samfurin.

· Motocin da suka dace sun haɗa da:

· Magani (mafi yawan amfani)

· Gel

· Man shafawa da man shafawa (dole ne a haɗa su cikin ruwa kafin a yi amfani da emulsification)

· Man shafawa mai hana ruwa

· Maganin fesawa

C) pH da Kwanciyar hankali:

· Mafi kyawun kewayon pH:5.0 – 7.0Tsarin da ke cikin wannan tsari yana tabbatar da daidaiton sinadarai da kuma dacewa da fata.

· A guji yanayin da ke da yawan acidic (pH < 4) ko alkaline (pH > 8) na tsawon lokaci.

D) Zafin jiki da Sarrafawa:

· Mai Sauƙin Zafi. Don hana lalacewa:

· Ƙara zuwa matakin ruwa a ko ƙasa da haka40°C (104°F).

· Mafi kyawun abin da za a ƙara shi ne bayan emulsion ɗin ya huce zuwa ƙasa da 40°C, ko kuma kawai a narkar da shi a cikin ruwan zafin ɗaki don yin amfani da serums/gels.

· A guji sarrafa zafin jiki mai yawa kamar cikewa mai zafi sai dai idan bayanan kwanciyar hankali sun tabbatar da hakan.

E) Sinadaran da suka dace da juna:

· Ya yi kyau sosai tare da: Sauran peptides masu hana tsufa (misali, Matrixyl, Argireline), hyaluronic acid, niacinamide, antioxidants (Bitamin C & E), masu sanyaya jiki.

· Haɗuwa Mai Haɗaka:

· Tare da wasu peptides na neuromodulating: Sau da yawa ana haɗa su da Acetyl Hexapeptide-8 (Argireline) don samun faffadan tasirin hana abubuwa da yawa.

· Tare da peptides masu ƙarfafa collagen: Haɗawa da peptides kamar Palmitoyl Tripeptide-1 ko Matrixyl yana magance layukan motsi (daga motsin tsoka) da layukan da ba sa motsi (daga asarar tallafin tsarin).

· Guji: Masu ƙarfi wajen samar da iskar oxygen ko rage yawan iskar oxygen. Yi taka tsantsan da wasu sinadarai masu ionic waɗanda ka iya shafar narkewar sa ko yanayin sa.

F) Kiyayewa:

· A matsayin sinadari mai narkewa cikin ruwa, tsarin ƙarshe yana buƙatar tsarin kiyayewa mai ƙarfi don hana haɓakar ƙwayoyin cuta wanda zai iya lalata peptide ɗin.