Candesartan CAS: 139481-59-7 Mai Bayar da Manufacturer

Candesartan zaɓi AT1 (angiotensin II receptor 1) antagonist.Antagonism na masu karɓar angiotensin yana hana vasoconstriction da samar da aldosterone, wanda ke haifar da raguwar ruwa da ƙwayar sodium a cikin jini.Yana nuna tasirin antihypertensive a cikin samfuran dabbobi.An yi amfani da shi wajen maganin cututtukan zuciya, a matsayin antihypertensive.Candesartan baya shafar iyawar kwayar halitta ko haɓakawa amma yana ƙara bayyanar VEGF da interleukin-8 a cikin al'adar ƙwayoyin KU-19-19.Candesartan (0.1 nM) zai iya rage mafi girman martanin kwangila ga angiostensin II da kusan 50%.