Acetylthiocholine iodide CAS:1866-15-5

Ana amfani da Acetylthiocholine iodide a matsayin wani abu da ake amfani da shi wajen auna aikin enzyme acetylcholinesterase (AChE). AChE ita ce ke da alhakin rushe acetylcholine mai aiki da neurotransmitter a cikin tsarin jijiyoyi. Ƙara acetylthiocholine iodide a cikin cakuda amsawar da ke ɗauke da AChE yana haifar da samar da thiocholine da acetate.

Ana iya gano martanin ta hanyar ƙara alamar launi ko fluorometric wanda ke amsawa musamman da thiocholine. Yawan samar da launi ko fluorescence yana daidai gwargwado kai tsaye da aikin AChE a cikin samfurin. Wannan ya sa acetylthiocholine iodide ya zama kayan aiki mai mahimmanci don auna ayyukan AChE a cikin samfuran halittu daban-daban, gami da kyallen takarda, al'adun ƙwayoyin halitta, da jini.

Ana amfani da ma'aunin ayyukan AChE ta amfani da acetylthiocholine iodide sosai a cikin binciken bincike da suka shafi tsarin cholinergic, cututtukan jijiyoyi, da kuma fallasa ga wasu sinadarai ko magunguna waɗanda ka iya shafar aikin AChE. Haka kuma ana iya amfani da shi azaman kayan aikin tantancewa don gano masu hana AChE, waɗanda ke da sha'awar haɓaka magunguna don cututtuka kamar Alzheimer's da Parkinson's.

Baya ga amfani da shi a cikin gwaje-gwajen enzymatic, ana iya amfani da acetylthiocholine iodide a matsayin madadin na'urorin nazarin halittu masu tushen AChE. An tsara waɗannan na'urorin nazarin halittu don gano da kuma auna kasancewar wasu abubuwa waɗanda za su iya hana ayyukan AChE, kamar magungunan kashe kwari na organophosphate ko magungunan jijiyoyi.