γ-L-Glutamyl-3-carboxy-4-nitroanilide, gishirin monoammonium CAS:63699-78-5

Gishirin monoammonium wani sinadari ne da ake amfani da shi a gwaje-gwajen sinadarai don gano da auna aikin enzyme γ-glutamyl transpeptidase (GGT). GGT wani sinadari ne da ake samu a cikin kyallen takarda daban-daban, ciki har da hanta, kodan, da pancreas. Yana da hannu wajen rushewa da kuma metabolism na glutathione, wani muhimmin sinadari mai hana tsufa a cikin ƙwayoyin halitta.

Ana canza mahaɗin ta hanyar GGT zuwa samfurin launin rawaya, wanda za'a iya auna shi ta hanyar spectrophotometric a wani takamaiman tsayin tsayi. Ƙarfin launin yana daidai da aikin GGT a cikin samfurin. Wannan yana ba da damar auna matakan aikin GGT, wanda zai iya taimakawa wajen tantance aikin hanta da kuma gano cututtukan hanta.

Amfani da gishirin γ-L-Glutamyl-3-carboxy-4-nitroanilide, a cikin gwaje-gwajen GGT yana da amfani a cikin yanayi daban-daban, gami da binciken asibiti, nazarin bincike, da haɓaka magunguna. Yana ba da damar sa ido kan ayyukan GGT a cikin samfuran marasa lafiya, yana ba da gudummawa ga gano da kimanta cututtukan hanta kamar cututtukan hanta na giya, ciwon daji na hanta, da lalacewar hanta da miyagun ƙwayoyi ke haifarwa.