Tirzepatide CAS: 2023788-19-2 Mai Bayar da Mai Karu

Tirzepatide CAS: 2023788-19-2 Mai Karu

An haɓaka Tirzepatide azaman agonist dual zuwa duka GLP-1 da masu karɓar polypeptide na ciki (GIP) (Frias et al., 2018).Hakazalika da GLP-1, GIP shine hormone incretin wanda ke aiki don haifar da ƙwayar insulin.Tirzepatide yana cikin ci gaba na kashi 3 na manya tare da kiba ko kiba tare da haɗuwa da nauyin nauyi kuma a halin yanzu yana ƙarƙashin bita na tsari a matsayin magani ga manya da nau'in ciwon sukari na 2. .Hakanan ana nazarinta azaman yuwuwar jiyya don cututtukan steatohepatitis mara-giya (NASH) da gazawar zuciya tare da ɓangarorin fitarwa da aka kiyaye (HFpEF).

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Ana amfani da Tirzepatide tare da ingantaccen tsarin abinci da motsa jiki don sarrafa hawan jini a cikin mutanen da ke da nau'in ciwon sukari na 2.Sarrafa yawan sukarin jini yana taimakawa hana lalacewar koda, makanta, matsalolin jijiya, asarar gabobin jiki, da matsalolin aikin jima'i.Tirzepatide yana da alaƙa mafi girma ga masu karɓar GIP fiye da masu karɓar GLP-1, kuma an nuna wannan hali na agonist dual don samar da raguwa mafi girma. na hyperglycemia idan aka kwatanta da zaɓin GLP-1 agonist mai karɓa.Nazarin siginar ya nuna cewa wannan saboda tirzepatide yana kwaikwayon ayyukan GIP na halitta a mai karɓar GIP.