Sitagliptin Phosphate CAS: 654671-78-0 Mai Karu

Sitagliptin Phosphate shine mai hana trizolopyrazine dipeptidyl peptidase IV mai hanawa.Sitagliptin an amince da shi kwanan nan don maganin ciwon sukari na II. Sitagliptin phosphate shine dipeptidyl peptidase Ⅳ (DDP-4) mai hanawa rukunin magungunan da kamfanin Merck na Jamus ya haɓaka kuma da farko ya sami amincewar Hukumar Abinci da Magunguna ta Amurka don kula da nau'in 2. ciwon sukari, wani sabon maganin ciwon sukari ne, yana iya inganta ikon jiki don rage yawan matakan glucose na jini, da kuma ƙara haɓakar haɓakar incretin ta dabi'a ta hanyar hana ayyukan wannan enzyme, gami da matakan glucagon-kamar peptide 1 da insulinotropic mai dogaro da glucose. peptide, don haka yana haifar da pancreas don inganta samar da insulin da kuma dakatar da samar da glucose a cikin hanta, kuma a ƙarshe ya rage tasirin tasirin glucose na jini.