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N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium gishiri CAS: 66992-27-6
N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium gishiri, wanda kuma aka sani da HEPES sodium gishiri, wani sinadaran fili da aka saba amfani da shi azaman pH buffering wakili a cikin nazarin halittu da kuma sinadaran dakunan gwaje-gwaje.Yana taimakawa wajen kiyaye tsayayyen pH, yana mai da shi manufa don aikace-aikace kamar al'adun tantanin halitta, ƙididdigar enzyme, nazarin furotin, electrophoresis, da ƙirar magunguna.HEPES sodium gishiri yana tabbatar da mafi kyawun yanayi don hanyoyin nazarin halittu kuma yana haɓaka daidaito da amincin sakamakon gwaji.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACIID SODIUM SALT CAS:76204-02-9
2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium gishiri wani sinadari ne da aka saba amfani dashi a cikin binciken bincike da bincike.Wani nau'in sialic acid ne da aka yi masa laƙabi, wani nau'in ƙwayoyin carbohydrate da ake samu a saman sel.
Ana amfani da wannan fili a matsayin wani abu don enzymes da ake kira neuraminidases, wanda ke aiki don cire ragowar sialic acid daga glycoproteins da glycolipids.Lokacin da waɗannan enzymes suka yi aiki akan 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium gishiri, yana fitar da samfurin mai kyalli wanda aka sani da 4-methylumbelliferone.
Za'a iya aunawa da ƙididdige hasken haske da ke haifar da fili, yana ba da bayani game da ayyukan enzymes neuraminidase.Wannan yana da amfani musamman a cikin nazarin cututtuka daban-daban da yanayin da ke hade da aberrant sialic acid metabolism.
Hakanan ana amfani da fili don dalilai na bincike, kamar a gano cututtukan ƙwayoyin cuta waɗanda ke haɗa aikin neuraminidase.A cikin waɗannan gwaje-gwajen, ana amfani da fili don gano kasancewar takamaiman ƙwayoyin cuta ko kuma tantance tasirin masu hana neuraminidase a cikin maganin rigakafi.
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TAPSO CAS: 68399-81-5 Farashin Mai samarwa
TAPSO (3-[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) wani buffer ne na zwitterionic wanda aka saba amfani dashi a cikin binciken nazarin halittu da kwayoyin halitta.Yana da ingantacciyar wakili mai buffer tare da pKa kusa da pH na jiki, yana mai da shi dacewa don kiyaye tsayayyen pH a cikin gwaje-gwajen nazarin halittu.Ana amfani da TAPSO sau da yawa a cikin tsarkakewar furotin, ƙididdigar enzyme, al'adun cell, da aikace-aikacen electrophoresis.Babban narkewar ruwa da ƙarancin tsangwama tare da hanyoyin nazarin halittu sun sa ya zama sanannen zaɓi a cikin al'ummar kimiyya.An san TAPSO don ƙarancin tasirinsa akan ayyukan enzyme kuma galibi ana amfani dashi azaman madadin sauran wakilai masu buffer kamar Tris ko phosphate buffers.
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N-Acetyl-L-cysteine CAS: 616-91-1
N-Acetyl-L-cysteine (NAC) wani nau'i ne na amino acid cysteine da aka gyara.Yana ba da tushen cysteine kuma ana iya jujjuya shi cikin sauri zuwa cikin glutathione tripeptide, mai ƙarfi antioxidant a cikin jiki.An san NAC don maganin antioxidant da kaddarorin mucolytic, yana sa ya zama mai amfani a aikace-aikacen lafiya daban-daban.
A matsayin antioxidant, NAC yana taimakawa kare sel daga lalacewa ta hanyar radicals kyauta, nau'in oxygen mai amsawa, da gubobi.Hakanan yana goyan bayan haɗakar glutathione, wanda ke taka muhimmiyar rawa a cikin ayyukan detoxification na jiki da kiyaye tsarin garkuwar jiki mai kyau.
An yi nazarin NAC don yuwuwar fa'idodinta a cikin lafiyar numfashi, musamman ga mutanen da ke da yanayi kamar mashako na yau da kullun, COPD, da cystic fibrosis.An fi amfani da shi azaman abin tsinkaya don taimakawa bakin ciki da sassauta gamsai, yana sauƙaƙa share hanyoyin iska.
Bugu da ƙari kuma, NAC ta nuna alƙawarin tallafawa lafiyar hanta ta hanyar taimakawa wajen kawar da abubuwa masu guba, irin su acetaminophen, mai maganin ciwo na kowa.Hakanan yana iya samun tasirin kariya daga lalacewar hanta ta hanyar shan barasa.
Baya ga kaddarorin tallafin antioxidant da na numfashi, an bincika NAC don yuwuwar fa'idodinta a cikin lafiyar hankali.Wasu bincike sun nuna cewa yana iya samun tasiri mai kyau a kan matsalolin yanayi, irin su baƙin ciki da damuwa mai tsanani (OCD).
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PIPES CAS: 5625-37-6 Farashin Mai ƙira
PIPES (piperazine-1,4-bisethanesulfonic acid) wani fili ne na buffering na zwitterionic wanda aka saba amfani dashi a cikin binciken nazarin halittu da kwayoyin halitta.Yana da tasiri mai mahimmanci na pH tare da babban ƙarfin don kiyaye yanayin pH a cikin kewayon pH na 6.1 zuwa 7.5.PIPES yana da ƙaramin tsangwama tare da kwayoyin halitta kuma ya dace da ƙididdigar dogaro da zafin jiki.Ana amfani da shi sau da yawa a cikin fasahar gel electrophoresis da ƙirar magunguna a matsayin wakili mai ƙarfafawa.Gabaɗaya, PIPES abu ne mai dacewa kuma ana amfani da shi sosai a cikin saitunan gwaji daban-daban.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4′-NHS ester wani nau'in sinadari ne tare da hadadden tsarin kwayoyin halitta.Ya ƙunshi ƙungiyar sulfopropylacridinium da ƙungiyar aikin ester carboxylate.Kasancewar ɓangarorin ester yana nuna cewa yana amsawa kuma ana iya amfani da shi azaman alamar lakabi ko gyaggyarawa don kwayoyin halitta.
Ƙungiyar sulfopropylacridinium na fili yana nuna cewa yana iya samun aikace-aikace masu yuwuwa a cikin gwaje-gwaje na tushen haske, inda za'a iya amfani da shi azaman bincike mai haske ko rini don ganowa da kuma nazarin kwayoyin halitta.Hakanan yana iya samun mahimmanci a cikin nazarin hanyoyin salula, kamar siginar calcium na cikin salula.
Haɗin ƙungiyar ester na NHS yana nuna cewa zai iya amsawa tare da amines na farko, kamar waɗanda aka samu a cikin furotin ko peptides, don samar da amintattun aminde.Wannan sake kunnawa yana sa ya zama mai amfani ga aikace-aikacen haɗin gwiwar halittu, inda za'a iya amfani da shi don yin lakabi ko gyara biomolecules tare da wasu kwayoyin aiki, kamar fluorophores ko tags.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide wani fili ne da aka yi amfani da shi a cikin nazarin nazarin halittu daban-daban, musamman don ganowa da hangen nesa na ayyukan enzyme.Abu ne mai sauƙi wanda za'a iya sanya shi ta hanyar takamaiman enzymes, wanda ke haifar da sakin samfur mai launi ko mai kyalli.
Ana amfani da wannan fili da yawa a cikin gwaje-gwaje don gano kasancewar da ayyukan enzymes kamar beta-galactosidase da beta-glucuronidase.Wadannan enzymes sun raba acetyl da glucosaminide kungiyoyin daga substrate, haifar da samuwar blue ko kore chromophore.
Tsarin musamman na 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide yana ba da damar gano sauƙi da ƙididdige ayyukan enzyme.Amfani da shi a cikin fasahohin gwaji daban-daban, gami da histochemistry, immunohistochemistry, da ƙididdigar tushen tantanin halitta, ya ba da gudummawa ga kyakkyawar fahimtar ayyukan enzyme.
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Sodium Gishiri Gishiri CAS: 139-41-3 Manufacturer Price
N, N-Bis (2-hydroxyethyl) glycine sodium gishiri wani sinadari ne da aka yi amfani da shi azaman wakili na buffering a cikin aikace-aikace daban-daban na biochemical da biophysical.Yana taimakawa daidaita matakin pH a cikin yanayin gwaji, yana mai da shi amfani a cikin nazarin enzyme, binciken furotin, al'adun tantanin halitta, da dabarun gogewa na Yamma.
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Spinosad CAS: 131929-60-7 Mai Bayar da Maƙera
Spinosad rukuni ne na 5 na nicotinic acetylcholine agonist mai karɓa, wanda ke haifar da ƙanƙancewar tsoka da rawar jiki na biyu zuwa kunna neuron.Tsawon bayyanarwa yana haifar da gurguzu da mutuwar ƙuma.Mutuwar ƙuma tana farawa a cikin mintuna 30 na allurai kuma a cikin awanni 4 ya cika.Spinosad baya mu'amala da wuraren dauri na wasu magungunan kashe kwari (GABA-ergic ko nicotinic).
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Rotenone CAS: 83-79-4 Mai Samfura
Rotenone duka ciki ne kuma gubar tuntuɓar arthropods.Ayyukan ƙwanƙwasa da sauri yana da alaƙa da raguwar samun nicotinamide adenine dinucleotide don yin aiki a matsayin mai haɗin gwiwa a cikin hanyoyin sinadarai daban-daban ciki har da sake zagayowar Krebs, don haka yana hana enzymes na numfashi na mitochondrial.
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Diazinon CAS: 333-41-5 Mai Bayar da Mai ƙira
Diazinon yana samuwa a cikin nau'i na ruwa mara launi ko duhu.Yana da ɗan narkewa cikin ruwa amma yana narkewa sosai a cikin ether mai, barasa, da benzene.Ana amfani da Diazinon don sarrafa nau'ikan noma da kwari iri-iri.Waɗannan sun haɗa da kwari a cikin ƙasa, akan tsire-tsire na ado, 'ya'yan itace, kayan marmari, da amfanin gona da kwari na gida kamar kwari, ƙuma, da kyankyasai.
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Avermectin CAS: 71751-41-2 Mai Bayar da Manufacturer
Abamectin (Avermectin) wakili ne mai guba mai guba.Tsarinsa yana yin niyya ga mai karɓar GABAA na ƙwayoyin ƙwayoyin cuta na ƙwayoyin cuta ko synapse neuromuscular, yana tsoma baki tare da canja wurin bayanan ƙarshen jijiyoyi, wato yana motsa ƙarshen jijiyoyi don sakin mai hana neurotransmitter γ-aminobutyric acid (GA-BA), yana haifar da buɗewar buɗe ido. GABA-gated chloride tashar tare da tasirin tashar chloride mai kunnawa.
