Mirabegron CAS: 223673-61-8 Mai Bayar da Mai Karu

Mirabegron CAS: 223673-61-8 Mai Bayar da Manufacturer

Mirabegron shine don maganin gaggawa, yawan fitsari, da rashin kwanciyar hankali na fitsari wanda ke hade da mafitsara mai aiki (OAB).An haɗa Mirabegron ta hanyar haɗa 4-nitrophenethyl amine zuwa (R) -2-hydroxy-2-phenylacetic acid.Sakamakon amide an rage shi zuwa amin.An rage rukunin nitro kuma sakamakon yana haɗe zuwa 2- (2-aminothiazol-4-yl) acetic acid don ba da mirabegron.

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Aikace-aikace da Tasiri

Mirabgron shine β3-adrenoceptor agonist a halin yanzu yana ci gaba ta hanyar Astellas Pharma don kula da mafitsara (OAB).Magungunan antagonist na nanomolar EC50 ne akan ƙididdigar ƙwayoyin cuta na β3-AR na ɗan adam tare da zaɓi mai kyau akan b1- da β2-ARs.Mirabegron yana nuna wani sabon tsari ta hanyar yin niyya ga β3-AR don shakatawa na mafitsara don taimakawa sarrafa alamun OAB kamar ƙara yawan gaggawar fitsari da mita da rashin daidaituwa na gaggawa.Koyaya, mirabegron shine mai hanawa na cytochrome P450 2D6, kuma yana haifar da damuwa game da hulɗar magunguna-magungunan tare da gudanarwar lokaci ɗaya na sauran cytochrome P450 2D6 substrates.

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Abun ciki	Saukewa: C21H24N4O2S
Assay	99%
Bayyanar	Fari zuwa Kodadde Yellow foda
CAS No.	223673-61-8
Shiryawa	25KG
Rayuwar Rayuwa	shekaru 2
Adana	Ajiye a wuri mai sanyi da bushewa
Takaddun shaida	ISO.