β-Nicotinamide Mononucleotide CAS: 1094-61-7

Ana amfani da β-Nicotinamide mononucleotide (NMN) don nazarin abubuwan ɗaure a cikin RNA aptamers da hanyoyin kunna ribozyme da suka haɗa da β-nicotinamide mononucleotide (β-NMN) -abubuwan RNA da aka kunna.NMN wani nucleotide ne wanda aka samo daga ribose da nicotinamide.Niacinamide (nicotinamide,) ya fito ne daga bitamin B3, wanda kuma aka sani da niacin.) A matsayin maƙasudin sinadarai na NAD+, yana iya zama da amfani wajen rigakafin pellagra.
β-Nicotinamide mononucleotide shine matsakaici a cikin biosynthesis na nicotinamide adenine dinucleotide (NAD+).Nicotinamide phosphoribosyltransferase (Nampt) yana haɓaka haɓakar nicotinamide tare da 5-phosphoribosyl-1-pyrophosphate don samar da β-NMN, wanda daga baya ya canza zuwa NAD + ta β-NMN adenyltransferase.At 50-100 an yi amfani da β-NMN zuwa NMN. NAD biosynthesis da glucose-stimulated insulin secretion a cikin samfurin Nampt +/- linzamin kwamfuta na cuta na rayuwa, yana nuna rawar Nampt a cikin aikin sel β.