3-Morpholino-2-hydroxypropanesulfonic acid sodium gishiri, kuma aka sani da MES sodium gishiri, wani sinadaran fili da aka saba amfani da matsayin buffering wakili a nazarin halittu da biochemical bincike.
MES wani buffer ne na zwitterionic wanda ke aiki azaman mai sarrafa pH, yana kiyaye pH a cikin tsarin gwaji daban-daban.Yana da matukar narkewa a cikin ruwa kuma yana da ƙimar pKa kusan 6.15, yana sa ya dace da buffering a cikin kewayon pH na 5.5 zuwa 7.1.
Ana yawan amfani da gishirin sodium na MES a cikin dabarun nazarin halittu kamar DNA da keɓewar RNA, ƙididdigar enzyme, da tsarkakewar furotin.Hakanan ana amfani dashi a cikin kafofin watsa labarai na al'adar tantanin halitta don kiyaye yanayin pH mai ƙarfi don haɓakar tantanin halitta da haɓakawa.
Ɗayan sanannen fasalin MES shine kwanciyar hankali a ƙarƙashin yanayin ilimin lissafi da juriya ga canje-canje a yanayin zafi.Wannan ya sa ya dace don amfani a gwaje-gwajen inda ake sa ran canjin yanayin zafi.
Masu bincike sukan fi son gishirin sodium na MES a matsayin mai karewa saboda ƙarancin tsangwama tare da halayen enzymatic da babban ƙarfin buffer a cikin kewayon pH mafi kyau.